OBJECTIVES: To describe the epidemiological profile of patients aged 60 years or older with AML treated at a referral hospital in the ABC region in Sao Paulo, Brazil, assessing the impact of the therapeutic strategy on the overall survival (OS) of this cohort. METHODs: Descriptive retrospective cohort study evaluating patients treated at Mario Covas State Hospital (HEMCO), for a period of 8 years, divided into groups according to the applied therapy. RESULTS: A total of 44 patients were evaluated. There were no significant differences in OS when groups of patients treated in an intensive and non-intensive way were compared. However, there was a strong tendency, in patients older than 70 years, to present better results when submitted to reduced doses of QT. Regarding mortality, in the first month it was slightly higher in the subgroup of intensive chemotherapy, reflecting mortality related to induction, but the values ??tend to be equal in the first year. CONCLUSION: The results obtained allow us to know the epidemiological profile and the evolution of the treatment in elderly patients diagnosed with AML treated in a reference unit for acute leukemia in a developing country.

OBJECTIVE: This work aims to obtain information on the opinion of health professionals and patients regarding the effects of animal assisted therapy/activity (AAT). METHODS: An opinion poll was conducted with the medical team (consisting of: doctors, nurses, psychologists) and patients (male and female gender over 18 years of age) on the use of animal assisted therapy through application through application of the questionnaire by the Google Forms platform, being applied only once; participants were selected for convenience. RESULTS: According to the groups surveyed 65.62% of participants reported already knowing AAT, being better known in the group of health professionals, among these 6.71% have already participated in some intervention of the type. In terms of risk/benefit to AAT, it gives more benefits than risk according to 75.03% of participants. Regarding species considered viable for the application of this therapy, 92.63%of participants believe that the dog would be the most appropriate animal, followed by the cat (66.84%) and the horse (55.66%). According to health professionals, children (90.5%), followed by elderly (87.1%) and autistic (73.6%) are the groups that benefited the most from AAT. CONCLUSION: Through this study it was possible to see that in the general population, men and women, the knowledge of animal assisted therapy is still little widespread when compared to health professionals. In addition, studies focused on proof of physiological benefits to the patient are still incipient and have limitations on the number of participants and methodology.

OBJECTIVE: To evaluate epidemiological, clinical, and prognostic profile of patients with acute vascular abdomen (AVA), framed as acute mesenteric ischemia (AMI) undergoing surgery. METHODS: Medical records of patients with AMI, who underwent surgery at Hospital Sancta Maggiore, São Paulo/SP, Brazil; between January 2017 to August 2021, were reviewed. For data analysis, the SPSS program version 18.0, independent Student t-test and Chi-square tests were used. RESULTS: Eighteen patients with a median age of 78 years were selected. The main personal history was hypertension and 63% reported severe abdominal pain on admission. 47% had door-to-surgery time less than 1 day, with surgical time less than 1 hour in 44% of cases. 31% stayed in the ward for more than 7 days and 40% stayed in the ICU for 1 to 3 days. 67% of the patients died. There were no significant differences between severe and extremely severe patients. In the elderly, AVA stands out as a rare condition with high mortality, tends to be more incident and may mimic acute abdomen: obstructive, inflammatory and/or perforative. CONCLUSION: AVA is a diagnostic and therapeutic challenge with likely future increased incidence. It is up to surgeons to obtain the necessary knowledge to diagnose and treat it to decrease its morbidity and mortality.

ABSTRACT OBJECTIVES: To identify the seroprevalence of asymptomatic individuals in areas of disease transmission and analyze the environmental, socioeconomic and demographic risk factors in the municipality of Petrolina/PE, Brazil. METHODS: We approached 92 individuals in 19 localities with VL cases recorded in the Information System for Notifiable Diseases (SINAN) between 2016 and 2017. In each visit, two questionnaires were applied seeking to obtain clinical, social, economic and environmental variables. Viable blood samples collected during the visits (n=90) were submitted to the Indirect Immunofluorescence Reaction to identify anti-Leishmania antibodies. For data analysis, descriptive statistical tests were performed using Stata® 14.0 software. RESULTS: The presence of antibodies was detected in 2.2% (2/90) of the samples, in which one individual presented symptoms and the other was classified as asymptomatic. No risk factors related to the presence of anti-Leishmania antibodies were identified. CONCLUSION: The identification of one asymptomatic individual reinforces the importance of expanding human prevalence studies in endemic areas. Despite the low prevalence, it was possible to identify a possible case with manifestation of the clinical form of chronic VL that needs proper care.

ABSTRACT OBJECTIVES: To review, identify, and describe the imaging features of congenital zika virus syndrome. METHODS: This is a review with emphasis on magnetic resonance (MRI) and its findings in the diagnosis of congenital zika virus syndrome. Articles, published in the last five years, were searched in PubMed databases. With the descriptors "Zika Virus Infection", "Zika Virus" and "Diagnostic imaging". RESULTS: Twenty-four articles that approached MRI as a complementary tool to ultrasound findings were analyzed. In the fetal period, it is considered better to evaluate abnormalities such as: polymicrogyria, opercular dysplasia, lisencephaly-pachygyria and ventriculomegaly. In the postnatal period it presents high sensitivity and specificity, being the method of choice in the late suspicion of congenital syndrome of ZIKV, in the images it is possible to visualize craniofacial disproportion, microcephaly, cerebral atrophy and reduction of cerebral cortical thickness. CONCLUSION: MRI shows as an important diagnostic method of morphological changes related to zika virus syndrome, contributing to the detailed study of congenital malformations, thus affecting maternal and child health and quality of life.